Volume 10, Issue 1 (2015) | American Journal of Pharmacology and Toxicology

Vascular Endothelial Growth Factor: An Overview Across Multiple Disease Conditions

Miriam Canavese — 2015-05-06

American Journal of Pharmacology and Toxicology, Published online: 6 May 2015; doi:10.3844/ajptsp.2015.1.12

Vascular Endothelial Growth Factor (VEGF) is the major player in the regulation of physiological angiogenesis as well as it has also been implicated in pathological angiogenesis, associated with cance...

Selected Genotoxic Impurities Profiling During WFI Qualification to Control Carcinogenesis in Large Volume Parenterals

Mohabbat Ullah — 2015-05-27

American Journal of Pharmacology and Toxicology, Published online: 27 May 2015; doi:10.3844/ajptsp.2015.13.26

Water For Injections (WFI) which is the main vehicle of Large Volume Parenterals (LVPs) should be free from trace amount of genotoxic impurities. This review gives emphasis on quantification of genoto...

Prescription Pattern of Anti-Hypertensive Drugs in Adherence to JNC- 7 Guidelines

Krishna Murti — 2015-06-02

American Journal of Pharmacology and Toxicology, Published online: 2 June 2015; doi:10.3844/ajptsp.2015.27.31

The main objective of the present study to investigate the utilization pattern of antihypertensive drugs in hypertensive patients and to find out whether the prescription pattern is in adherence with ...

Effects of Recombinant Toxin Phospholipase D in Cardiac Muscle of Rats

Joao Victor Capelli Peixoto — 2015-06-02

American Journal of Pharmacology and Toxicology, Published online: 2 June 2015; doi:10.3844/ajptsp.2015.32.36

Loxoceles spiders gender are worldwide spread and its bites can cause dermonecrosis or even a systemic effect (hemolysis, kidney and liver injury). It is believed that phospholipase D, the main compon...