Volume 9, Issue 2 (2014) | American Journal of Pharmacology and Toxicology

EVALUATION OF THE ANTI-ARTHRITIC EFFECT OF STERCULIA TRAGACANTHA (LINDL.) LEAF EXTRACT IN RATS

Udegbunam Rita Ijeoma — 2014-03-11

American Journal of Pharmacology and Toxicology, Published online: 11 March 2014; doi:10.3844/ajptsp.2014.107.113

Sterculia tragacantha leaves for years have been used by traditional healers in eastern Nigeria in the treatment of arthritis, edema, gout, whitlow and cold. The aim of this study was to evaluate the ...

STUDIES ON GASTROINTESTINAL EFFECTS OF DESMODIUM VELUTINUM: A TRADITIONAL REMEDY FOR DIARRHEA

A. C. Ezike — 2014-03-12

American Journal of Pharmacology and Toxicology, Published online: 12 March 2014; doi:10.3844/ajptsp.2014.114.124

The gastrointestinal and antibacterial properties of dichloromethane: Methanol extract (DVE) and fractions (DVHF, DVDF and DVMF) from Desmodium velutinum Willd. DC. (Fabaceae) leaves were investigated...

MELATONIN PROTECTS THE INTEGRITY OF GASTRIC STRUCTURE FROM A STERILE TISSUE INJURY AND AUGMENTS BOTH MONONUCLEAR AND POLYMORPHONUCLEAR PERIPHERAL BLOOD CELLS INDUCED BY THE INJURY IN WISTAR ALBINO RATS

Bahjat Al-Ani — 2014-03-17

American Journal of Pharmacology and Toxicology, Published online: 17 March 2014; doi:10.3844/ajptsp.2014.125.131

Peptic ulcer is a common upper gastrointestinal disease that remains a major public health problem. Gastric ulceration caused by Nonsteroidal Anti-Inflammatory Drugs (NSAID), stress and alcohol are th...

ANTICONVULSANT AND NEUROTOXICITY EVALUATION OF SOME NEWLY SYNTHESIZED THIAZOLYL COUMARIN DERIVATIVES

M. Faiz Arshad — 2014-03-26

American Journal of Pharmacology and Toxicology, Published online: 26 March 2014; doi:10.3844/ajptsp.2014.132.138

The present series of compounds were synthesized with the aim to develop newer anticonvulsant agents that are comparatively more efficacious and safer than the currently used anticonvulsant agents. Va...

COMPARATIVE STUDY OF ANTIBACTERIAL ACTIVITY OF PLANT EXTRACTS FROM SEVERAL REGIONS OF ASIA

Awatif Al-Judaibi — 2014-04-02

American Journal of Pharmacology and Toxicology, Published online: 2 April 2014; doi:10.3844/ajptsp.2014.139.147

This study was designed to investigate the antibacterial activities of alcohol extracts of Phoenix dactylifera (date palm ’type Ajwa’), Nigella sativa (black cumin), Elettaria cardamomum (cardamom...

ANTIOPHIDIAN ACTIVITY OF BROSIMUM GUIANENSE (AUBL) HUBER

Jose Adolfo Homobono Machado Bittencourt — 2014-05-13

American Journal of Pharmacology and Toxicology, Published online: 13 May 2014; doi:10.3844/ajptsp.2014.148.156

Snakebites envenomations are a problem public health in worldwide due to the high rates of morbidity and mortality. The Bothrops venom causes local tissue damage and inflammation is one of the most im...

THE IMPACT OF ANTIOXIDANTS ON INFLAMMATION AND OXIDATIVE STRESS MARKERS IN OSTEOARTHRITIS RAT MODEL: SCANNING ELECTRON MICROSCOPE INSIGHTS

El Hassan Heidar — 2014-05-19

American Journal of Pharmacology and Toxicology, Published online: 19 May 2014; doi:10.3844/ajptsp.2014.157.167

Osteoarthritis (OA) is characterized by degradation of matrix and destruction of articular cartilage. Articular chondrocytes are solely responsible for the production and maintenance of the extracellu...

THE INFLUENCE OF PERSONALITY ACCENTUATION ON DRUG ADDICTION AMONG STUDENTS

Elena Aleksandrovna Cheverikina — 2014-06-27

American Journal of Pharmacology and Toxicology, Published online: 27 June 2014; doi:10.3844/ajptsp.2014.168.173

To identify character accentuation students who are prone to addiction will allow to adjust their socialization process during the training period in order to increase its effectiveness, as well as it...