Volume 8, Issue 4 (2013) | American Journal of Pharmacology and Toxicology

Combined Chelation Therapy with Deferasirox and Desferrioxamine In Removing Lead from Rats

Faezeh Dahooee Balooch — 2013-09-24

American Journal of Pharmacology and Toxicology, Published online: 24 September 2013; doi:10.3844/ajptsp.2013.134.140

The present study aimed to evaluate the potential efficiency of Deferasirox (DFX) and Desfferioxamine (DFO) as chelating agents in removing lead from rats as a biological model. Two different doses of...

Hepatoprotective Effect of N-Acetylcystiene on the Toxic Hazards of titanium Dioxide Nanoparticles

Hossam Fouad Attia — 2013-09-26

American Journal of Pharmacology and Toxicology, Published online: 26 September 2013; doi:10.3844/ajptsp.2013.141.147

The present study was directed to evaluate the toxic effects of orally administered titanium dioxide naonparticles (TiO2) on liver of male albino rats and to evaluate the ameliorative effects of N-ace...

Toxicity of Zinc Oxide Nanoparticles in Lung Tissue After Repeated Oral Administration

Ataollah Shokouhian — 2013-10-21

American Journal of Pharmacology and Toxicology, Published online: 21 October 2013; doi:10.3844/ajptsp.2013.148.154

Pathological experiments should be considered following oral administration of ZnO. Effect of different doses of ZnO nanoparticle on LDH in oral method showed significant differences in control group ...

Community Pharmacists’ Involvement in Breast Cancer Health Promotion in United Arab Emirates (UAE)

Osama H. Mohamed Ibrahim — 2013-10-29

American Journal of Pharmacology and Toxicology, Published online: 29 October 2013; doi:10.3844/ajptsp.2013.155.163

Breast cancer is the most common cancer in women in Middle East countries. Despite the continuous efforts to increase the public awareness of breast cancer via campaigns and public screening programs,...

Effect of Chromium(VI) on Serum Iron and Removal of its Toxicity by Combining Deferasirox and Deferiprone Chelators in Rats

S. Jamil A. Fatemi — 2013-10-30

American Journal of Pharmacology and Toxicology, Published online: 30 October 2013; doi:10.3844/ajptsp.2013.164.169

The present research is aimed to characterize the potential efficiency of two chelators after chromium(VI) administration for 60 days following two doses of 15 and 30 mg kg-1 chromium(VI) per body wei...

Effect of Streptozotocin-Induced Hyperglycemia on the Progression of Hepatocarcinogenesis in Rats

Chowdhury Mobaswar Hossain — 2013-11-04

American Journal of Pharmacology and Toxicology, Published online: 4 November 2013; doi:10.3844/ajptsp.2013.170.178

Diabetes mellitus and hepatocellular carcinoma both have detrimental impact on health worldwide. Type II diabetes and liver cancer share many causative factors, but biological correlation between the ...

Ethanolic Extract of Leaves of Newbouldia laevis Attenuates Glycosylation of Hemoglobin and Lipid Peroxidation in Diabetic Rats

Kolawole O. Timothy — 2013-11-13

American Journal of Pharmacology and Toxicology, Published online: 13 November 2013; doi:10.3844/ajptsp.2013.179.186

Diabetes is one of the major health problems around the world and the incidence of this metabolic disorder is on the increase. Current therapeutic interventions have not done much in preventing compli...

Antiretroviral Toxicity and Oxidative Stress

Adikwu Elias — 2013-11-20

American Journal of Pharmacology and Toxicology, Published online: 20 November 2013; doi:10.3844/ajptsp.2013.187.196

Antiretroviral drugs are used for the treatment of human immunodeficiency virus, they are used as combination regimens to achieve the highest possible benefit, tolerability, compliance and to diminish...

Adiponectin Regulation in Type 2 Diabetic Rats: Effects of Insulin, Metformin and Dexamethasone

Tamer Ahmed Ismail — 2013-11-23

American Journal of Pharmacology and Toxicology, Published online: 23 November 2013; doi:10.3844/ajptsp.2013.197.208

Adiponectin is a protein synthesized from adipose tissue, increases peripheral glucose utilization in liver and skeletal muscle. Adiponectin expression and secretion are decreased during obesity and i...

Effect of Green Tea on Hepatic Cells Under the Influence of Inflammatory Conditions: In Vitro Study

Ibrahim G. Saleh — 2013-12-03

American Journal of Pharmacology and Toxicology, Published online: 3 December 2013; doi:10.3844/ajptsp.2013.209.217

The concern about safety of consumption of Green Tea (GT) supplements has become a scope of many studies. We and others have described earlier the effect of the administration of GT and its polyphenol...