Volume 7, Issue 2 (2012) | American Journal of Pharmacology and Toxicology

Bilirubin Lowering Potential of Annona muricata (Linn.) In Temporary Jaundiced Rats

Fareed K.N. Arthur — 2012-05-23

American Journal of Pharmacology and Toxicology, Published online: 23 May 2012; doi:10.3844/ajptsp.2012.33.40

Problem statement: Annona muricata is used in Ghanaian traditional medicine for the treatment of jaundice. Work done has demonstrated A. muricata to be effective in treating carbon tetrachloride-and a...

Assessment of Neuropharmacological Activities of Terminalia Chebula in Rats

Wathita Phachonpai — 2012-06-11

American Journal of Pharmacology and Toxicology, Published online: 11 June 2012; doi:10.3844/ajptsp.2012.41.48

Problem statement: Oxidative stress has been implicated in the pathophysiology of many neurodegenerative diseases such as Alzheimer’s Disease (AD). In traditional practices of Ayurvedic medicine, nu...

Effect of New Compound with Antioxidant Potential in the Energy Metabolism of Adults Rats after Pneumococcal Meningitis

T. Barichello — 2012-06-15

American Journal of Pharmacology and Toxicology, Published online: 15 June 2012; doi:10.3844/ajptsp.2012.49.61

Problem statement: In bacterial meningitis, the Streptococcus pneumoniae can modify the cerebro-spinal fluid (CSF) homeostasis and initiation of the host inflammatory response with presence cytokine a...

Toxicological Evaluation of Murraya Paniculata (L.) Leaves Extract on Rodents

R. K. Goel — 2012-07-09

American Journal of Pharmacology and Toxicology, Published online: 9 July 2012; doi:10.3844/ajptsp.2012.62.67

Problem statement: Present study was aimed to explore the acute and sub-acute toxicities studies with orally administered 50% ethanolic leaves extract of Murraya paniculata. Approach: Acute toxicity (...

Quercetin in Dimethyl Benzanthracene Induced Breast Cancer in Rats

Natla Sashidhar Reddy — 2012-07-30

American Journal of Pharmacology and Toxicology, Published online: 30 July 2012; doi:10.3844/ajptsp.2012.68.72

Problem statement: Vincristine a commonly used anticancer agent in the treatment of breast cancer results in serious adverse effects like teratogenicity, neurotoxicity and carcinogenicity on long term...

Gastroprotective Effect and Safety Assessment of Zanthoxylum Zanthoxyloides (Lam) Waterm Root Bark Extract

Alex Boye — 2012-08-07

American Journal of Pharmacology and Toxicology, Published online: 7 August 2012; doi:10.3844/ajptsp.2012.73.80

Problem statement: Gastrointestinal ulcers account significantly for morbidity and mortality in Ghana. The study therefore investigated the gastroprotective effect of an ethanolic root bark extract of...