Volume 5, Issue 1 (2010) | American Journal of Pharmacology and Toxicology

Mutagenic Screening of Crude Oil Fractions Using Modified Ames Test and Allium cepa (Linn) Assay

Olufunsho Awodele — 2010-01-31

American Journal of Pharmacology and Toxicology, Published online: 31 January 2010; doi:10.3844/ajptsp.2010.1.8

Problem statement: Crude oil which may be broadly characterized as paraffinic or naphthenic is a complex mixture of alkanes, cycloalkanes and aromatic hydrocarbons. About 500,000 workers are employed ...

Risk Assessment of Tobacco Types and Oral Cancer

Abdoul Hossain Madani — 2010-03-31

American Journal of Pharmacology and Toxicology, Published online: 31 March 2010; doi:10.3844/ajptsp.2010.9.13

Problem statement: Oral cancer is one of the most common life threatening cancers all over the world, in particular Asian countries and tobacco is considered to be the most potent risk factor for oral...

Hypolipidemic Effects of Coenzyme Q10 in Experimentally Induced Hypercholesterolemic Model in Female Rats

Atef M. Al-Attar — 2010-03-31

American Journal of Pharmacology and Toxicology, Published online: 31 March 2010; doi:10.3844/ajptsp.2010.14.23

Problem statement: Hyperlipidemia is well known to play a main role in the development of atherosclerosis. It is characterized by abnormally elevated cholesterol, triglyceride, low density lipoprotein...

Quercetin, Quercetrin Except Rutin Potentially Increased Pirarubicin Cytotoxicity by Non-Competitively Inhibiting the P-Glycoprotein-and MRP1 Function in Living K562/adr and GLC4/adr Cells

Winit Choiprasert — 2010-03-31

American Journal of Pharmacology and Toxicology, Published online: 31 March 2010; doi:10.3844/ajptsp.2010.24.33

Problem statement: Quercetin and its glycoside derivatives are increasingly receiving interests as new generation of anticancer molecules and were recognized by multidrug resistant transporters such a...

Taurine Implicated in Bromocriptine Induced Hallucination: Glycine-Glutamic-Aspartic Implicated in Bromocriptine Induced Schizophrenia

Abdulrahim Abu Jayyab — 2010-03-31

American Journal of Pharmacology and Toxicology, Published online: 31 March 2010; doi:10.3844/ajptsp.2010.34.41

Problem statement: The literature is reviewed and supports a strong anecdotal relationship between bromocriptine use and psychosis. It is well known that any interference with brain amino acid levels ...

Safety Assessment of Herbal Formulations, Rumbion™ and Tyrel™ in Albino Wistar Rats

A.J. Joshua — 2010-03-31

American Journal of Pharmacology and Toxicology, Published online: 31 March 2010; doi:10.3844/ajptsp.2010.42.47

Problem statement: Herbal remedies form one of the effective strategies for management of livestock healthcare. Despite the availability of extensive pharmacological information, the toxicological dat...

Interaction between Cadmium and Calcium in Human Blood at the Smokers

Lulzim Zeneli — 2010-03-31

American Journal of Pharmacology and Toxicology, Published online: 31 March 2010; doi:10.3844/ajptsp.2010.48.51

Problem statement: Defining of correlation between toxic and essential elements in human beings is an important clinical screening procedure. Approach: The aim of this study was to determine the corre...

Characterization of Nigella Sativa L. Essential Oil-Loaded Solid Lipid Nanoparticles

Nagi A. ALHaj — 2010-03-31

American Journal of Pharmacology and Toxicology, Published online: 31 March 2010; doi:10.3844/ajptsp.2010.52.57

Problem statement: Seeds of Nigella Sativa L., commonly known as black seed, have been used in traditional medicine by many Asian, Middle Eastern and Far Eastern Countries to treat headache, coughs, a...