Volume 1, Issue 1 (2006) | American Journal of Pharmacology and Toxicology

Antitussive Activity Directed Isolation of Compounds from Onosma hispidum

Shahina Naz — 2006-03-31

American Journal of Pharmacology and Toxicology, Published online: 31 March 2006; doi:10.3844/ajptsp.2006.1.4

The chemical investigation of the ethanolic extract of the root bark of Onosma hispidum following antitussive activity directed isolation led to the isolation of 4-hydroxy-3-methoxy cinnamic acid (mCA...

Effects of Administration of Alpha-Melanocyte Stimulating Hormone (α-MSH) on Some Hematological Values of Alloxan-induced Diabetic Rats

Kamal M.S. Mansi — 2006-03-31

American Journal of Pharmacology and Toxicology, Published online: 31 March 2006; doi:10.3844/ajptsp.2006.5.10

This study was designed to evaluate the role of alpha- melanocyte stimulating hormone (α-MSH) on heart rate and some hematological values in alloxan induced diabetic rats. 40 male white rats were div...

Clozapine and its Major Stable Metabolites, N-desmethylclozapine and Clozapine N-oxide do not Affect Human Bone Marrow Stromal Cells in vitro

Avril Pereira — 2006-03-31

American Journal of Pharmacology and Toxicology, Published online: 31 March 2006; doi:10.3844/ajptsp.2006.11.16

Treatment of refractory schizophrenia with the atypical antipsychotic drug clozapine is associated with life-threatening agranulocytosis, characterised by a drop in neutrophil count. Theoretically, to...

Hepatoprotective Activity of Aqueous Ethanolic Extract of Chamomile capitula in Paracetamol Intoxicated Albino Rats

Ajay k. Gupta — 2006-03-31

American Journal of Pharmacology and Toxicology, Published online: 31 March 2006; doi:10.3844/ajptsp.2006.17.20

Hepatoprotective activity of aqueous ethanolic extract of Chamomile recutita capitula against paracetamol induced hepatic damage in albino rats was observed. In the present study the effect of aqueous...