Volume 5, Issue 2 (2009) | American Journal of Infectious Diseases

In vitro and In vivo Antioxidant Activity of Aphanamixis polystachya Bark

Alluri V. Krishnaraju — 2009-06-30

American Journal of Infectious Diseases, Published online: 30 June 2009; doi:10.3844/ajidsp.2009.60.67

Problem statement: Free radical stress leads to tissue injury and progression of disease conditions such as arthritis, hemorrhagic shock, atherosclerosis, diabetes, hepatic injury, aging and ische...

Anti-Inflammatory Activity of Vitex leucoxylon L. Bark Extracts Against Freund's Complete Adjuvant Induced Arthritis in Sprague Dawley Rat

Alluri V. Krishnaraju — 2009-06-30

American Journal of Infectious Diseases, Published online: 30 June 2009; doi:10.3844/ajidsp.2009.68.73

Problem statement: Anti-inflammatory agents, particularly steroids and cyclooxygenase inhibitors are often associated with adverse side effects including, GI irritation, ulcers, hypertension and c...

Identification of Clonal Clusters of Klebsiella pneumoniae Isolates from Chennai by Extended Spectrum Beta Lactamase Genotyping and Antibiotic Resistance Phenotyping Analysis

C. Kamatchi — 2009-06-30

American Journal of Infectious Diseases, Published online: 30 June 2009; doi:10.3844/ajidsp.2009.74.82

Problem statement: An increased resistance to antibiotics has been reported in Klebsiella pneumoniae, an opportunistic gram negative pathogen belonging to Entrobacteraceae due to the evolution and...

Synthesis of Coenzyme Q₁₀

Suryachandra Rao Ravada — 2009-06-30

American Journal of Infectious Diseases, Published online: 30 June 2009; doi:10.3844/ajidsp.2009.83.89

Problem statement: CoQ10 is a key compound in ATP synthesis having wide number of health application especially for treating humans suffering from pathophysiological condition. The CoQ10 presently...

Cytotoxic and Antimicrobial Potential of Actinomycete Species Saccharopolyspora salina VITSDK4 Isolated from the Bay of Bengal Coast of India

K. Suthindhiran — 2009-06-30

American Journal of Infectious Diseases, Published online: 30 June 2009; doi:10.3844/ajidsp.2009.90.98

Problem statement: Although the diversity of marine Actinobacteria have been studied and biotechnologically exploited throughout the world, the studies on marine actinobacteria in Indian peninsula...

Protective Effect of Enicostemma littorale Blume on Rat Model of Diabetic Neuropathy

Niraj Mukundray Bhatt — 2009-06-30

American Journal of Infectious Diseases, Published online: 30 June 2009; doi:10.3844/ajidsp.2009.99.105

Problem statement: Poor glycemic control and oxidative stress is implicated as a common pathway in the development of diabetic neuropathy. Approach: In the present study, we investigated the prote...

Comparison of Bleeding Time and Clotting Time in Different Blood Groups

B. Mahapatra — 2009-06-30

American Journal of Infectious Diseases, Published online: 30 June 2009; doi:10.3844/ajidsp.2009.106.108

Problem statement: Researchers have demonstrated that epistaxis is more often encountered in patients having blood group O probably due to lower expression of von Willebrand factor. We had taken u...

Almond Consumption Decreases Fasting and Post Prandial Blood Glucose Level in Female Type 2 Diabetes Subject

Parul Choudhary — 2009-06-30

American Journal of Infectious Diseases, Published online: 30 June 2009; doi:10.3844/ajidsp.2009.109.111

Problem statement: Population studies indicate that individuals who regularly consume nuts have reduced risk for cardiovascular diseases and diabetes. The beneficial role of almonds has been estab...

Isolation and Characterization of Potential Probiotic Escherichia coli Strains from Rat Faecal Samples

Prasant Kumar — 2009-06-30

American Journal of Infectious Diseases, Published online: 30 June 2009; doi:10.3844/ajidsp.2009.112.117

Problem statement: Gastrointestinal disorders mainly diarrhea is the most common cause of morbidity and mortality among infants and children in the developing countries occurs due to infection by ente...

Influence of Quercetin on Diabetes-Induced Alteration in CYP3A Activity and Bioavailability of Pioglitazone in Rats

Sudhir Niranjan Umathe — 2009-06-30

American Journal of Infectious Diseases, Published online: 30 June 2009; doi:10.3844/ajidsp.2009.118.125

Problem statement: Quercetin-a common bioflavonoid, is present in herbal preparations consumed by diabetic patients along with routine anti-diabetic agents. We recently showed that quercetin incre...

Intrinsically Unstructured Proteins: Potential Targets for Drug Discovery

Pathan Salma — 2009-06-30

American Journal of Infectious Diseases, Published online: 30 June 2009; doi:10.3844/ajidsp.2009.126.134

Problem statement: The function of a protein is dependent on its three-dimensional structure. However, numerous proteins lacking intrinsic globular 3D structure under physiological conditions had ...

The Flavonoid, Quercetin, Inhibits HIV-1 Infection in Normal Peripheral Blood Mononuclear Cells

Madhavan P.N. Nair — 2009-06-30

American Journal of Infectious Diseases, Published online: 30 June 2009; doi:10.3844/ajidsp.2009.135.141

Problem statement: Flavonoids and related polyphenols, have been known to possess cardioprotective, anti-tumor, anti-inflammatory, anti-allergic and anti-viral activities. Previous studies have shown ...

Target Identification in Ory S1 Pollen Protein Allergen from Oryza sativa in the Course of Construction of Hypoallergenic Vaccines

Ruchi Sharma — 2009-06-30

American Journal of Infectious Diseases, Published online: 30 June 2009; doi:10.3844/ajidsp.2009.142.147

Problem statement: Recombinant-based approaches are mostly focused on genetic modification of allergens to produce molecules with reduced allergenic activity and conserved antigenicity, such as hy...

Molecular Characterization of Opium Poppy (Papaver somniferum) Germplasm

Hari Shanker Acharya — 2009-06-30

American Journal of Infectious Diseases, Published online: 30 June 2009; doi:10.3844/ajidsp.2009.148.153

Problem statement: The medicinal value of opium poppy (2n = 22, Papaver somniferum L.) is due to presence of more than two dozen alkaloids. The genetic origin and diversity of cultivars used in th...

Effect of Aqueous Extract of Aegle marmelos Fruit on Adherence and β-Lactam Resistance of Enteropathogenic Escherichia coli by Down Regulating Outer Membrane Protein C

Subramaniya Bharathi Raja — 2009-06-30

American Journal of Infectious Diseases, Published online: 30 June 2009; doi:10.3844/ajidsp.2009.154.162

Problem statement: Enteropathogenic Escherichia Coli (EPEC) continue to be a major health problem, leading to death due to diarrhea, predominantly in children below the age of five. Due to evolution o...

Molecular Analysis of Coagulase Gene Polymorphism in Clinical Isolates of Methicilin Resistant Staphylococcus aureus by Restriction Fragment Length Polymorphism Based Genotyping

M. Himabindu — 2009-06-30

American Journal of Infectious Diseases, Published online: 30 June 2009; doi:10.3844/ajidsp.2009.163.169

Problem statement: To investigate coagulase gene variants through Restriction Fragment Length Polymorphism (RFLP) amongst clinical isolates of Methicillin-Resistant Staphylococcus Aureus (MRSA) co...